Double Shut-Off Couplings & Tubing for Pharmaceutical Dosing Equipment

Pharmaceutical dosing equipment meters controlled quantities of liquid or gas into a process, container or analytical system. Detachable connections can simplify module changes and maintenance, but the connector must be selected around the actual medium and process requirements.

lab technician in a hairnet and coat watches an automated bottling line with small bottles on a conveyor.

Where are couplings used on pharmaceutical dosing equipment?

Depending on the machine, tubing can connect reservoirs, dosing modules, pumps, valves and service circuits. A quick-release connection can provide a removable interface between a fixed machine connection and a replaceable hose or dosing module.

Kee supplies coupling and tubing components, not the dosing machine. Any pharmaceutical-contact, cleaning or validation requirement must be established by the equipment manufacturer or process owner.

How does the system work?

Medium supply

The process medium is supplied from a reservoir or service line.

Dosing control

Pumps, valves or metering components control the required quantity.

Transfer

Tubing carries the medium to the dosing point.

Module change

A detachable connection can allow a hose or dosing module to be removed for service or changeover.

Where do Kee couplings, fittings and tubing fit?

Where residual fluid on disconnection needs to be reduced, a double shut-off coupling can be considered because both the coupling and plug contain valves. The suitability of that valve arrangement still depends on the machine and process.

What matters when selecting the connection?

Medium compatibility

Body and seal materials must be checked against the actual pharmaceutical or process fluid.

Residual fluid

Valve arrangement can influence how much medium is released during disconnection.

Cleanability

The connector design must fit the equipment's cleaning and validation approach.

Small-bore accuracy

Tube and connector dimensions should support the required dosing circuit without creating an inappropriate restriction.

Kee 327 Series for this application

The Kee 327 Series is a miniature 2.7 mm double shut-off coupling. Kee's catalogue specifically records frequent use in medical technology and chemistry/pharmacy. The double shut-off arrangement retains the medium on both sides when disconnected, making the range relevant for investigation where a compact valved interface is required.

327 Series | Double Shut Off Quick Release Couplings & Plugs

Nominal Diameter 2.7mm
Two metal hydraulic/pneumatic quick-connect fittings with knurled grips and threaded bases on a white background.

Mini industrial double shut off coupling with numerous application options with various media. Frequent use in medical technology and chemistry/pharmacy. Retains medium in both sides when disconnected.

Coupling Specifications

Back Body: Brass (MS 58)

Valve Body: Brass (MS 58)

Sleeve: Brass (MS 58)

Spring: Stainless Steel 301

Locking Balls: Stainless Steel 301

Plug Specifications

Plug Body: Brass (MS 58)

Valve: Brass (MS 58)

Body: Brass (MS 58)

Spring: Stainless Steel 301

Seal: NBR

View the complete Kee 327 Series

Available 327 Series configurations

The table below is pulled directly from the Kee catalogue data so current part numbers and available configurations remain tied to the live series information.

Male Thread BSPP Coupling

Part Number Termination (mm) Length (mm) Diameter (mm)
327CDMM50BNX M5 26mm 10mm
327CDMP18BNX 1/8" 28mm 10mm

Female Thread BSPP Coupling

Part Number Termination (mm) Length (mm) Diameter (mm)
327CDFM50BNX M5 26mm 10mm
327CDFP18BNX 1/8" 28mm 10mm

Hosetail Coupling

Part Number Termination (mm) Length (mm) Diameter (mm)
327CDHT03BNX 3mm 35mm 10mm
327CDHT04BNX 4mm 35mm 10mm
327CDHT05BNX 5mm 35mm 10mm

Bulkhead To Tube Coupling

Part Number Termination (mm) Length (mm) Diameter (mm)
327CDBT04BNX 3mm 45mm 10mm
327CDBT05BNX 5mm 45mm 10mm
327CDBT06BNX 6mm 45mm 10mm

Tube Connection Coupling

Part Number Temination Length (mm) Diameter (mm)
327CDTC04BNX 3 x 4mm 33mm 10mm
327CDTC05BNX 3 x 5mm 33mm 10mm
327CDTC06BNX 3 x 6mm 33mm 10mm

Bulkhead To Hosetail Coupling

Part Number Termination (mm) Length (mm) Diameter (mm)
327CDBH03BNX 3mm 51mm 10mm
327CDBH04BNX 4mm 51mm 10mm
327CDBH06BNX 6mm 51mm 10mm

Male Thread BSPP Plug

Part Number Termination (mm) Length (mm)
327PDMM50BNX m5 28mm
327PDMP18BNX 1/8" 30mm

Female Thread BSPP Plug

Part Number Termination (mm) Length (mm)
327PDFM50BNX m5 26mm
327PDFP18BNX 1/8" 30mm

Hosetail Plug

Part Number Termination (mm) Length (mm)
327PDHT03BNX 3mm 36mm
327PDHT04BNX 4mm 36mm
327PDHT05BNX 5mm 36mm

Bulkhead To Tube Plug

Part Number Termination (mm) Length (mm)
327PDBT04BNX 3 x 4mm 47mm
327PDBT05BNX 3 x 5mm 47mm
327PDBT06BNX 3 x 6mm 47mm

Tube Connection Plug

Part Number Termination (mm) Length (mm)
327PDTC04BNX 3 x 4mm 31mm
327PDTC05BNX 3 x 5mm 31mm
327PDTC06BNX 3 x 6mm 31mm

Bulkhead To Hose Tail Plug

Part Number Termination (mm) Length (mm)
327PDBH03BNX 3mm 53mm
327PDBH04BNX 4mm 53mm
327PDBH06BNX 6mm 53mm

327 connection options for dosing equipment

The 327 range includes small threaded, hose-tail, tube and bulkhead terminations. Selection should be based on the actual dosing line dimensions, medium, pressure, temperature and process requirements.

Process and validation considerations

Catalogue availability does not establish pharmaceutical-contact approval. Any material certification, cleanability, sterilisation or validation requirement must be confirmed for the specific equipment and process.

Kee can review coupling, seal and tubing requirements against the information supplied by the OEM or process engineer.

Why this connection approach is relevant

The 327 Series combines a miniature format with valves on both coupling and plug and is directly referenced by Kee for chemistry/pharmacy applications. It is therefore a relevant range to investigate where the process requirements suit that design.

OEM, replacement and assembly support

Kee Connections can support OEMs, equipment builders and maintenance teams with individual couplings, plugs, fittings and tubing or with configured hose and coupling assemblies. For replacement work, photographs, plug-profile dimensions, thread or tube dimensions and operating conditions provide a useful starting point for technical review.

For new equipment, Kee can review the connection point and help determine an appropriate valve arrangement, termination, material and assembly before samples or production quantities are specified.

FAQs

What is a double shut-off coupling?

Both the coupling and plug contain valves that open when connected and close when disconnected, helping retain medium on both sides.

Is the Kee 327 Series approved for every pharmaceutical process?

No. Process suitability, material requirements and any required approvals or validation must be established for the actual application.

Can Kee supply hose or tubing with the coupling?

Kee can support configured hose and coupling assemblies where the required tubing, termination and test criteria are defined.

author avatar
Kee Connections Team UK OEM Manufacturer of Quick Release Couplings
Kee Connections is a UK-based OEM manufacturer specialising in quick release couplings, hose assemblies and fluid transfer components, operating from Burscough, Lancashire.

References to Rectus®, CEJN®, Hansen®, PCL®, Tema®, Walther®, ARO®, Schrader®, Lüdecke®, Hasco®, and other third-party manufacturers, together with their product series, model numbers and trademarks, are provided solely for product identification, compatibility and interchangeability guidance.

Kee Connections Ltd is not affiliated with, endorsed by, sponsored by, or authorised by any of these manufacturers unless expressly stated. All trademarks, registered trademarks and product names remain the property of their respective owners.

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