Double Shut-Off Couplings & Tubing for Pharmaceutical Dosing Equipment
Pharmaceutical dosing equipment meters controlled quantities of liquid or gas into a process, container or analytical system. Detachable connections can simplify module changes and maintenance, but the connector must be selected around the actual medium and process requirements.

Where are couplings used on pharmaceutical dosing equipment?
Depending on the machine, tubing can connect reservoirs, dosing modules, pumps, valves and service circuits. A quick-release connection can provide a removable interface between a fixed machine connection and a replaceable hose or dosing module.
Kee supplies coupling and tubing components, not the dosing machine. Any pharmaceutical-contact, cleaning or validation requirement must be established by the equipment manufacturer or process owner.
How does the system work?
Medium supply
The process medium is supplied from a reservoir or service line.
Dosing control
Pumps, valves or metering components control the required quantity.
Transfer
Tubing carries the medium to the dosing point.
Module change
A detachable connection can allow a hose or dosing module to be removed for service or changeover.
Where do Kee couplings, fittings and tubing fit?
Where residual fluid on disconnection needs to be reduced, a double shut-off coupling can be considered because both the coupling and plug contain valves. The suitability of that valve arrangement still depends on the machine and process.
What matters when selecting the connection?
Medium compatibility
Body and seal materials must be checked against the actual pharmaceutical or process fluid.
Residual fluid
Valve arrangement can influence how much medium is released during disconnection.
Cleanability
The connector design must fit the equipment's cleaning and validation approach.
Small-bore accuracy
Tube and connector dimensions should support the required dosing circuit without creating an inappropriate restriction.
Kee 327 Series for this application
The Kee 327 Series is a miniature 2.7 mm double shut-off coupling. Kee's catalogue specifically records frequent use in medical technology and chemistry/pharmacy. The double shut-off arrangement retains the medium on both sides when disconnected, making the range relevant for investigation where a compact valved interface is required.
327 Series | Double Shut Off Quick Release Couplings & Plugs

Mini industrial double shut off coupling with numerous application options with various media. Frequent use in medical technology and chemistry/pharmacy. Retains medium in both sides when disconnected.
Coupling Specifications
Back Body: Brass (MS 58)
Valve Body: Brass (MS 58)
Sleeve: Brass (MS 58)
Spring: Stainless Steel 301
Locking Balls: Stainless Steel 301
Plug Specifications
Plug Body: Brass (MS 58)
Valve: Brass (MS 58)
Body: Brass (MS 58)
Spring: Stainless Steel 301
Seal: NBR
View the complete Kee 327 Series
Available 327 Series configurations
The table below is pulled directly from the Kee catalogue data so current part numbers and available configurations remain tied to the live series information.
Male Thread BSPP Coupling
| Part Number | Termination (mm) | Length (mm) | Diameter (mm) |
|---|---|---|---|
| 327CDMM50BNX | M5 | 26mm | 10mm |
| 327CDMP18BNX | 1/8" | 28mm | 10mm |
Female Thread BSPP Coupling
| Part Number | Termination (mm) | Length (mm) | Diameter (mm) |
|---|---|---|---|
| 327CDFM50BNX | M5 | 26mm | 10mm |
| 327CDFP18BNX | 1/8" | 28mm | 10mm |
Hosetail Coupling
| Part Number | Termination (mm) | Length (mm) | Diameter (mm) |
|---|---|---|---|
| 327CDHT03BNX | 3mm | 35mm | 10mm |
| 327CDHT04BNX | 4mm | 35mm | 10mm |
| 327CDHT05BNX | 5mm | 35mm | 10mm |
Bulkhead To Tube Coupling
| Part Number | Termination (mm) | Length (mm) | Diameter (mm) |
|---|---|---|---|
| 327CDBT04BNX | 3mm | 45mm | 10mm |
| 327CDBT05BNX | 5mm | 45mm | 10mm |
| 327CDBT06BNX | 6mm | 45mm | 10mm |
Tube Connection Coupling
| Part Number | Temination | Length (mm) | Diameter (mm) |
|---|---|---|---|
| 327CDTC04BNX | 3 x 4mm | 33mm | 10mm |
| 327CDTC05BNX | 3 x 5mm | 33mm | 10mm |
| 327CDTC06BNX | 3 x 6mm | 33mm | 10mm |
Bulkhead To Hosetail Coupling
| Part Number | Termination (mm) | Length (mm) | Diameter (mm) |
|---|---|---|---|
| 327CDBH03BNX | 3mm | 51mm | 10mm |
| 327CDBH04BNX | 4mm | 51mm | 10mm |
| 327CDBH06BNX | 6mm | 51mm | 10mm |
Male Thread BSPP Plug
| Part Number | Termination (mm) | Length (mm) |
|---|---|---|
| 327PDMM50BNX | m5 | 28mm |
| 327PDMP18BNX | 1/8" | 30mm |
Female Thread BSPP Plug
| Part Number | Termination (mm) | Length (mm) |
|---|---|---|
| 327PDFM50BNX | m5 | 26mm |
| 327PDFP18BNX | 1/8" | 30mm |
Hosetail Plug
| Part Number | Termination (mm) | Length (mm) |
|---|---|---|
| 327PDHT03BNX | 3mm | 36mm |
| 327PDHT04BNX | 4mm | 36mm |
| 327PDHT05BNX | 5mm | 36mm |
Bulkhead To Tube Plug
| Part Number | Termination (mm) | Length (mm) |
|---|---|---|
| 327PDBT04BNX | 3 x 4mm | 47mm |
| 327PDBT05BNX | 3 x 5mm | 47mm |
| 327PDBT06BNX | 3 x 6mm | 47mm |
Tube Connection Plug
| Part Number | Termination (mm) | Length (mm) |
|---|---|---|
| 327PDTC04BNX | 3 x 4mm | 31mm |
| 327PDTC05BNX | 3 x 5mm | 31mm |
| 327PDTC06BNX | 3 x 6mm | 31mm |
Bulkhead To Hose Tail Plug
| Part Number | Termination (mm) | Length (mm) |
|---|---|---|
| 327PDBH03BNX | 3mm | 53mm |
| 327PDBH04BNX | 4mm | 53mm |
| 327PDBH06BNX | 6mm | 53mm |
327 connection options for dosing equipment
The 327 range includes small threaded, hose-tail, tube and bulkhead terminations. Selection should be based on the actual dosing line dimensions, medium, pressure, temperature and process requirements.
Process and validation considerations
Catalogue availability does not establish pharmaceutical-contact approval. Any material certification, cleanability, sterilisation or validation requirement must be confirmed for the specific equipment and process.
Kee can review coupling, seal and tubing requirements against the information supplied by the OEM or process engineer.
Why this connection approach is relevant
The 327 Series combines a miniature format with valves on both coupling and plug and is directly referenced by Kee for chemistry/pharmacy applications. It is therefore a relevant range to investigate where the process requirements suit that design.
OEM, replacement and assembly support
Kee Connections can support OEMs, equipment builders and maintenance teams with individual couplings, plugs, fittings and tubing or with configured hose and coupling assemblies. For replacement work, photographs, plug-profile dimensions, thread or tube dimensions and operating conditions provide a useful starting point for technical review.
For new equipment, Kee can review the connection point and help determine an appropriate valve arrangement, termination, material and assembly before samples or production quantities are specified.
FAQs
What is a double shut-off coupling?
Both the coupling and plug contain valves that open when connected and close when disconnected, helping retain medium on both sides.
Is the Kee 327 Series approved for every pharmaceutical process?
No. Process suitability, material requirements and any required approvals or validation must be established for the actual application.
Can Kee supply hose or tubing with the coupling?
Kee can support configured hose and coupling assemblies where the required tubing, termination and test criteria are defined.

